Love & Other Drugs

Love & Other Drugs (2010)

Addicted to one-night stands or dependent on one another?

Release:2010
Runtime:1h 52m
Country:United States
Director:Edward Zwick
Language:English

Genre

ComedyDramaRomance
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Keywords

LetterSexual FreedomloveViagraFree SpiritParkinson S DiseasePills

Love & Other Drugs rating: IMDb, Rotten Tomatoes and Metacritic

IMDb6.7/10· 241K votes
Rotten Tomatoes49%
Metacritic55%
TMDb7.044/10· 6K votes

With 49% on Rotten Tomatoes, backed by 6.7/10 on IMDb and 55/100 on Metacritic, critical reception of this film has been modest.

About Love & Other Drugs

Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.

Cast of Love & Other Drugs

  • Jake Gyllenhaal

    Jake Gyllenhaal

    as Jamie Randall

  • Anne Hathaway

    Anne Hathaway

    as Maggie Murdock

  • Oliver Platt

    Oliver Platt

    as Bruce Winston

  • Hank Azaria

    Hank Azaria

    as Dr. Stan Knight

  • Josh Gad

    Josh Gad

    as Josh Randall

  • Gabriel Macht

    Gabriel Macht

    as Trey Hannigan

  • Judy Greer

    Judy Greer

    as Cindy

  • Jill Clayburgh

    Jill Clayburgh

    as Nancy Randall

  • George Segal

    George Segal

    as Dr. James Randall

  • Kate Jennings Grant

    Kate Jennings Grant

    as Gina

  • Katheryn Winnick

    Katheryn Winnick

    as "Lisa"

  • Kimberly Scott

    Kimberly Scott

    as Gail

Love & Other Drugs facts

Budget
$30M
Box office
$102.8M

Our take on Love & Other Drugs

Edward Zwick's 2010 romantic comedy-drama pairs Maggie, a free spirit determined never to be tied down, with Jamie, a charming pharmaceutical salesman whose easy confidence works on women and clients alike. Their sparring attraction deepens into something neither expected, set against the sharp-elbowed world of drug sales in the late 1990s. The film blends adult romance with a lightly satirical look at the pharmaceutical industry, giving its leads room for both banter and vulnerability. Viewers who like their love stories grown-up, funny and unafraid of complication are the target; those wanting a chaste, tidy romance should note its frankness about sex and illness. A likable, adult-leaning date-night pick.

Ranked by the iRankMovies editorial teamUpdated August 2026MethodologyData sources

Audience opinions

What the audience liked

  • Romantic chemistry between leads elevates formulaic dramedy
  • Serious health crisis subplot adds genuine emotional weight
  • Balances humor and heart throughout relationship exploration

What the audience disliked

  • Formulaic romantic comedy structure undermines serious subject matter
  • Tonal shifts between comedy and drama feel jarring and forced

Trailer

Where to watch Love & Other Drugs(US)

View on JustWatch

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