
Love & Other Drugs (2010)
Addicted to one-night stands or dependent on one another?
Keywords
Love & Other Drugs rating: IMDb, Rotten Tomatoes and Metacritic
With 49% on Rotten Tomatoes, backed by 6.7/10 on IMDb and 55/100 on Metacritic, critical reception of this film has been modest.
About Love & Other Drugs
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
Cast of Love & Other Drugs

Jake Gyllenhaal
as Jamie Randall

Anne Hathaway
as Maggie Murdock

Oliver Platt
as Bruce Winston

Hank Azaria
as Dr. Stan Knight

Josh Gad
as Josh Randall

Gabriel Macht
as Trey Hannigan

Judy Greer
as Cindy

Jill Clayburgh
as Nancy Randall

George Segal
as Dr. James Randall

Kate Jennings Grant
as Gina

Katheryn Winnick
as "Lisa"

Kimberly Scott
as Gail
Love & Other Drugs facts
- Budget
- $30M
- Box office
- $102.8M
Our take on Love & Other Drugs
Edward Zwick's 2010 romantic comedy-drama pairs Maggie, a free spirit determined never to be tied down, with Jamie, a charming pharmaceutical salesman whose easy confidence works on women and clients alike. Their sparring attraction deepens into something neither expected, set against the sharp-elbowed world of drug sales in the late 1990s. The film blends adult romance with a lightly satirical look at the pharmaceutical industry, giving its leads room for both banter and vulnerability. Viewers who like their love stories grown-up, funny and unafraid of complication are the target; those wanting a chaste, tidy romance should note its frankness about sex and illness. A likable, adult-leaning date-night pick.
Ranked by the iRankMovies editorial teamUpdated August 2026MethodologyData sources
Audience opinions
What the audience liked
- •Romantic chemistry between leads elevates formulaic dramedy
- •Serious health crisis subplot adds genuine emotional weight
- •Balances humor and heart throughout relationship exploration
What the audience disliked
- •Formulaic romantic comedy structure undermines serious subject matter
- •Tonal shifts between comedy and drama feel jarring and forced
Trailer
Where to watch Love & Other Drugs(US)
View on JustWatch →Rent / Buy
Availability may change. Data by JustWatch.
Looking for movies similar to Love & Other Drugs?
We've ranked 50 similar movies using 8 weighted content dimensions.