Splice (2010)
She's not human...not entirely.
Keywords
Splice rating: IMDb, Rotten Tomatoes and Metacritic
IMDb5.8/10· 106K votes
Rotten Tomatoes75%
Metacritic66%
TMDb5.875/10· 2K votesWith 75% on Rotten Tomatoes, backed by 5.8/10 on IMDb and 66/100 on Metacritic, critical reception of this film has been positive.
About Splice
Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.
Cast of Splice
Adrien Brody
as Clive
Sarah Polley
as Elsa
Delphine Chanéac
as Dren
David Hewlett
as Barlow
Abigail Chu
as Young Dren
Stephanie Baird
as Elsa / PD
Brandon McGibbon
as Gavin
Amanda Brugel
as Melinda Finch
Simona Măicănescu
as Joan Chorot
Splice facts
- Budget
- $26M
Ranked by the iRankMovies editorial teamUpdated August 2026MethodologyData sources
Audience opinions
What the audience liked
- •Body horror and genetic experimentation create thoroughly disturbing atmosphere
- •Visceral sci-fi concepts explore absurd and distressing ethical dilemmas
- •Directors distinctive visual approach generates strong emotional reactions
What the audience disliked
- •Lower IMDb score reflects divisive reception despite critical appreciation
- •Extreme content may alienate mainstream audiences seeking conventional sci-fi
Trailer
Where to watch Splice(US)
View on JustWatch →Rent / Buy
Google Play Movies
YouTubeAvailability may change. Data by JustWatch.
Looking for movies similar to Splice?
We've ranked 50 similar movies using 8 weighted content dimensions.