
50 Movies Like The Substance (2024) You Need to Watch Next
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Updated June 2026
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If you loved The Substance (2024) by Coralie Fargeat, here are 50 movies that share its content DNA. iRankMovies measures real similarity using cosine similarity across eight weighted dimensions — genre (50%), tone (12%), pace (10%), structure (8%), era (7%), theme (6%), audience (4%) and narrative perspective (3%) — not just the rating. The closest matches according to our analysis are 28 Years Later, The Long Walk, 28 Weeks Later. Every title is ranked by how closely it matches and backed by the iRank Score, a composite of IMDb, Rotten Tomatoes, Metacritic and TMDb across 12,000+ analysed titles.
50 Movies Similar to The Substance

28 Years Later
2025 · Danny Boyle
Twenty-eight years after the Rage virus outbreak, a heavily-defended island survives connected to the mainland by a single causeway. When one of the group leaves the island into the dark heart of the
In common: Horror · Science Fiction · Thriller

The Long Walk
2025 · Francis Lawrence
In a dystopian 1970s America, fifty teenage boys take part in a deadly annual walking contest, forced to maintain a minimum pace or be executed, until only one survivor remains.
In common: Horror · Science Fiction · Thriller

28 Weeks Later
2007 · Juan Carlos Fresnadillo
Twenty-eight weeks after the spread of a deadly rage virus, the inhabitants of the British Isles have lost their battle against the onslaught, as the virus has killed everyone there. Six months later,
In common: Horror · Science Fiction · Thriller

The Fly
1986 · David Cronenberg
When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and
In common: Horror · Science Fiction

The Invisible Man
2020 · Leigh Whannell
When Cecilia's abusive ex takes his own life and leaves her his fortune, she suspects his death was a hoax. As a series of coincidences turn lethal, Cecilia works to prove that she is being hunted by
In common: Horror · Science Fiction · Thriller

The Platform 2
2024 · Galder Gaztelu-Urrutia
After a mysterious leader imposes his law in a brutal system of vertical cells, a new arrival battles against a dubious food distribution method.
In common: Horror · Science Fiction · Thriller

Night of the Living Dead
1968 · George A. Romero
A ragtag group barricade themselves in an old Pennsylvania farmhouse to remain safe from a horde of flesh-eating ghouls ravaging the Northeast.
In common: Horror · Science Fiction · Thriller

When Evil Lurks
2023 · Demián Rugna
When brothers Pedro and Jimi discover that a demonic infection has been festering in a nearby farmhouse, they attempt to evict the victim from their land. Failing to adhere to the proper rites of exor
In common: Horror · Thriller

Godzilla
1954 · Ishirō Honda
Japan is thrown into a panic after several ships are sunk near Odo Island. An expedition to the island led by Dr. Kyohei Yamane soon discover something far more devastating than imagined in the form o
In common: Horror · Science Fiction · Thriller

28 Years Later: The Bone Temple
2026 · Nia DaCosta
Dr. Kelson finds himself in a shocking new relationship - with consequences that could change the world as they know it - and Spike's encounter with Jimmy Crystal becomes a nightmare he can't escape.
In common: Horror · Science Fiction · Thriller

Wolf Man
2025 · Leigh Whannell
With his marriage fraying, Blake persuades his wife Charlotte to take a break from the city and visit his remote childhood home in rural Oregon. As they arrive at the farmhouse in the dead of night, t
In common: Horror · Thriller

Eraserhead
1977 · David Lynch
First-time father Henry Spencer tries to survive his industrial environment, his angry girlfriend, and the unbearable screams of his newly born mutant child.
In common: Horror · Science Fiction

The Cell
2000 · Tarsem Singh
A psychotherapist journeys inside a comatose serial killer in the hopes of saving his latest victim.
In common: Horror · Science Fiction · Thriller

Companion
2025 · Drew Hancock
During a weekend getaway at a secluded lakeside estate, a group of friends finds themselves entangled in a web of secrets, deception, and advanced technology. As tensions rise and loyalties are tested
In common: Horror · Science Fiction · Thriller

Subservience
2024 · SK Dale
With his wife out sick, a struggling father brings home a lifelike AI, only to have his self-aware new help want everything her new family has to offer... Like the affection of her owner and she'll ki
In common: Horror · Science Fiction · Thriller

10 Cloverfield Lane
2016 · Dan Trachtenberg
After a catastrophic car crash, a young woman wakes up in a survivalist's underground bunker, where he claims to have saved her from an apocalyptic attack that has left the outside world uninhabitable
In common: Horror · Science Fiction

The Mist
2007 · Frank Darabont
After a violent storm, a dense cloud of mist envelops a small Maine town, trapping David Drayton and his five-year-old son in a local grocery store with other local residents. They soon discover that
In common: Horror · Science Fiction · Thriller

Annihilation
2018 · Alex Garland
A biologist signs up for a dangerous, secret expedition into a mysterious zone where the laws of nature don't apply.
In common: Horror · Science Fiction

A Quiet Place: Day One
2024 · Michael Sarnoski
As New York City is invaded by alien creatures who hunt by sound, a woman named Sam fights to survive with her cat.
In common: Horror · Science Fiction · Thriller

Signs
2002 · M. Night Shyamalan
A family living on a farm finds mysterious crop circles in their fields which suggests something more frightening to come.
In common: Horror · Science Fiction · Thriller

Old
2021 · M. Night Shyamalan
A group of families on a tropical holiday discover that the secluded beach where they are staying is somehow causing them to age rapidly – reducing their entire lives into a single day.
In common: Horror · Thriller

The Faculty
1998 · Robert Rodriguez
When some very creepy things start happening around school, the kids at Herrington High make the chilling discovery that confirms their worst suspicions: their teachers really are from another planet!
In common: Horror · Science Fiction

Immaculate
2024 · Michael Mohan
An American nun embarks on a new journey when she joins a remote convent in the Italian countryside. However, her warm welcome quickly turns into a living nightmare when she discovers her new home har
In common: Horror · Thriller

Arcadian
2024 · Benjamin Brewer
In the near future, on a decimated Earth, Paul and his twin sons face terror at night when ferocious creatures awaken. When Paul is nearly killed, the boys come up with a plan for survival, using ever
In common: Horror · Science Fiction

Men
2022 · Alex Garland
In the aftermath of a personal tragedy, Harper retreats alone to the beautiful English countryside, hoping to find a place to heal. But someone — or something — from the surrounding woods appears to b
In common: Horror · Thriller

Evil Dead Rise
2023 · Lee Cronin
A reunion between two estranged sisters gets cut short by the rise of flesh-possessing demons, thrusting them into a primal battle for survival as they face the most nightmarish version of family imag
In common: Horror · Thriller

The Purge
2013 · James DeMonaco
Given the country's overcrowded prisons, the U.S. government begins to allow 12-hour periods of time in which all illegal activity is legal. During one of these free-for-alls, a family must protect th
In common: Horror · Science Fiction · Thriller

The Thing
2011 · Matthijs van Heijningen Jr.
When paleontologist Kate Lloyd travels to an isolated outpost in Antarctica for the expedition of a lifetime, she joins an international team that unearths a remarkable discovery. Their elation quickl
In common: Horror · Science Fiction

Land of the Dead
2005 · George A. Romero
The living dead have taken over the world, and the remaining humans live in a walled city to protect themselves as they cope with the situation.
In common: Horror · Science Fiction · Thriller

Abigail
2024 · Matt Bettinelli-Olpin
A group of criminals kidnap a teenage ballet dancer, the daughter of a notorious gang leader, in order to obtain a ransom of $50 million, but over time, they discover that she is not just an ordinary
In common: Horror · Thriller

Thrash
2026 · Tommy Wirkola
When a Category 5 hurricane decimates a coastal town, the storm surge brings devastation, chaos, and something far more frightening onto shore: hungry sharks.
In common: Horror · Thriller

Alien: Romulus
2024 · Fede Álvarez
While scavenging the deep ends of a derelict space station, a group of young space colonizers come face to face with the most terrifying life form in the universe.
In common: Horror · Science Fiction

The Sadness
2021 · Rob Jabbaz
A young couple is pushed to the limits of sanity as they attempt to be reunited amid the chaos of a pandemic outbreak. The streets erupt into violence and depravity, as those infected are driven to en
In common: Horror · Thriller

The Human Centipede (First Sequence)
2009 · Tom Six
During a stopover in Germany in the middle of a carefree road trip through Europe, two American girls find themselves alone at night when their car breaks down in the woods. Searching for help at a ne
In common: Horror

Dawn of the Dead
2004 · Zack Snyder
A group of survivors take refuge in a shopping mall after the world is taken over by aggressive, flesh-eating zombies.
In common: Horror · Science Fiction

Ring
1998 · Hideo Nakata
A mysterious video has been linked to a number of deaths, and when an inquisitive journalist finds the tape and views it herself, she sets in motion a chain of events that puts her own life in danger.
In common: Horror · Thriller

Heretic
2024 · Scott Beck
Two young missionaries are forced to prove their faith when they knock on the wrong door and are greeted by a diabolical Mr. Reed, becoming ensnared in his deadly game of cat-and-mouse.
In common: Horror · Thriller

Brightburn
2019 · David Yarovesky
What if a child from another world crash-landed on Earth, but instead of becoming a hero to mankind, he proved to be something far more sinister?
In common: Horror · Science Fiction

Hidden
2015 · Ross Duffer
A family takes refuge in a fallout shelter to avoid a dangerous outbreak.
In common: Horror · Thriller

I Saw the Devil
2010 · Kim Jee-woon
Kyung-chul is a dangerous psychopath who kills for pleasure. Soo-hyeon, a top-secret agent, decides to track down the murderer himself. He promises himself that he will do everything in his power to t
In common: Horror · Thriller

Speak No Evil
2024 · James Watkins
When an American family is invited to spend the weekend at the idyllic country estate of a charming British family they befriended on vacation, what begins as a dream holiday soon warps into a snarled
In common: Horror · Thriller

Strange Darling
2024 · JT Mollner
Nothing is what it seems when a twisted one-night stand spirals into a serial killer’s vicious murder spree.
In common: Horror · Thriller

Thir13en Ghosts
2001 · Steve Beck
Arthur and his two children inherit his uncle's estate: a glass house that serves as a prison to twelve ghosts. When the family, accompanied by a nanny and an attorney, enter the house they find thems
In common: Horror · Thriller

Drag Me to Hell
2009 · Sam Raimi
After denying a woman the extension she needs to keep her home, loan officer Christine Brown sees her once-promising life take a startling turn for the worse. Christine is convinced she's been cursed
In common: Horror · Thriller

The Omen
1976 · Richard Donner
Immediately after their miscarriage, the US diplomat Robert Thorn adopts the newborn Damien without the knowledge of his wife. Yet what he doesn’t know is that their new son is the son of the devil.
In common: Horror · Thriller

Splice
2010 · Vincenzo Natali
Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "
In common: Horror · Science Fiction

Dangerous Animals
2025 · Sean Byrne
A savvy and free-spirited surfer is abducted by a shark-obsessed serial killer. Held captive on his boat, she must figure out how to escape before he carries out a ritualistic feeding to the sharks be
In common: Horror · Thriller

30 Days of Night
2007 · David Slade
This is the story of an isolated Alaskan town that is plunged into darkness for a month each year when the sun sinks below the horizon. As the last rays of light fade, the town is attacked by a bloodt
In common: Horror · Thriller

Fresh
2022 · Mimi Cave
Frustrated by scrolling dating apps only to end up on lame, tedious dates, Noa takes a chance by giving her number to the awkwardly charming Steve after a produce-section meet-cute at the grocery stor
In common: Horror · Thriller

Crawl
2019 · Alexandre Aja
When a huge hurricane hits her hometown in Florida, Haley ignores evacuation orders to look for her father. After finding him badly wounded, both are trapped by the flood. With virtually no time to es
In common: Horror · Thriller