50 Movies Like Slither (2006) You Need to Watch Next
A small town is taken over by an alien plague, turning residents into zombies and all forms of mutant monsters.
Updated June 2026
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If you loved Slither (2006) by James Gunn, here are 50 movies that share its content DNA. iRankMovies measures real similarity using cosine similarity across eight weighted dimensions — genre (50%), tone (12%), pace (10%), structure (8%), era (7%), theme (6%), audience (4%) and narrative perspective (3%) — not just the rating. The closest matches according to our analysis are Critters, The Faculty, The Return of the Living Dead. Every title is ranked by how closely it matches and backed by the iRank Score, a composite of IMDb, Rotten Tomatoes, Metacritic and TMDb across 12,000+ analysed titles.
50 Movies Similar to Slither
Critters
1986 · Stephen Herek
Carnivorous aliens arrive unannounced at a Kansas family farm; two intergalactic bounty hunters soon follow, determined to blow them off the planet.
In common: Comedy · Horror · Science Fiction
The Faculty
1998 · Robert Rodriguez
When some very creepy things start happening around school, the kids at Herrington High make the chilling discovery that confirms their worst suspicions: their teachers really are from another planet!
In common: Horror · Science Fiction
The Return of the Living Dead
1985 · Dan O'Bannon
When two bumbling employees at a medical supply warehouse accidentally release a deadly gas into the air, the vapors cause the dead to rise again as zombies.
In common: Comedy · Horror · Science Fiction
Killer Klowns from Outer Space
1988 · Stephen Chiodo
Aliens disguised as clowns crash land on Earth in a rural town to capture unsuspecting victims in cotton candy cocoons for later consumption.
In common: Comedy · Horror · Science Fiction
Nope
2022 · Jordan Peele
Residents in a lonely gulch of inland California bear witness to an uncanny, chilling discovery.
In common: Horror · Science Fiction
The Fly
1986 · David Cronenberg
When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and
In common: Horror · Science Fiction
The Rocky Horror Picture Show
1975 · Jim Sharman
After getting a flat tire in the middle of nowhere, newly engaged couple Brad and Janet encounter the eerie mansion of the flamboyant, seductive Dr Frank-N-Furter and a variety of eccentric characters
In common: Comedy · Horror · Science Fiction
Eraserhead
1977 · David Lynch
First-time father Henry Spencer tries to survive his industrial environment, his angry girlfriend, and the unbearable screams of his newly born mutant child.
In common: Horror · Science Fiction
Lilo & Stitch
2025 · Dean Fleischer Camp
The wildly funny and touching story of a lonely Hawaiian girl and the fugitive alien who helps to mend her broken family.
In common: Comedy · Science Fiction
The Thing
1982 · John Carpenter
A research team in Antarctica is hunted by a shape-shifting alien that assumes the appearance of its victims.
In common: Horror · Science Fiction
The Ugly Stepsister
2025 · Emilie Blichfeldt
In a fairy-tale kingdom where beauty is a brutal business, Elvira battles to compete with her incredibly beautiful stepsister, and she will go to any length to catch the prince’s eye.
In common: Comedy · Horror
Annihilation
2018 · Alex Garland
A biologist signs up for a dangerous, secret expedition into a mysterious zone where the laws of nature don't apply.
In common: Horror · Science Fiction
The Thing
2011 · Matthijs van Heijningen Jr.
When paleontologist Kate Lloyd travels to an isolated outpost in Antarctica for the expedition of a lifetime, she joins an international team that unearths a remarkable discovery. Their elation quickl
In common: Horror · Science Fiction
Tremors
1990 · Ron Underwood
Val McKee and Earl Bassett are in a fight for their lives when they discover that their desolate town has been infested with gigantic, man-eating creatures that live below the ground.
In common: Comedy · Horror
Death Becomes Her
1992 · Robert Zemeckis
Madeline is married to Ernest, who was once her arch-rival Helen's fiancé. After recovering from a mental breakdown, Helen vows to kill Madeline and steal back Ernest. Unfortunately for everyone, the
In common: Comedy · Horror
A Quiet Place: Day One
2024 · Michael Sarnoski
As New York City is invaded by alien creatures who hunt by sound, a woman named Sam fights to survive with her cat.
In common: Horror · Science Fiction
Signs
2002 · M. Night Shyamalan
A family living on a farm finds mysterious crop circles in their fields which suggests something more frightening to come.
In common: Horror · Science Fiction
Species
1995 · Roger Donaldson
In 1993, the Search for Extra Terrestrial Intelligence Project receives a transmission detailing an alien DNA structure, along with instructions on how to splice it with human DNA. The result is Sil,
In common: Horror · Science Fiction
Paul
2011 · Greg Mottola
For the past 60 years, a space-traveling smart-ass named Paul has been locked up in a top-secret military base, advising world leaders about his kind. But when he worries he’s outlived his usefulness
In common: Comedy · Science Fiction
PK
2014 · Rajkumar Hirani
A stranger in the city asks questions no one has asked before. Known only by his initials, the man's innocent questions and childlike curiosity take him on a journey of love, laughter and letting go.
In common: Comedy · Science Fiction
The Substance
2024 · Coralie Fargeat
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
In common: Horror · Science Fiction
Bugonia
2025 · Yorgos Lanthimos
Two conspiracy obsessed young men kidnap the high-powered CEO of a major company, convinced that she is an alien intent on destroying planet Earth.
In common: Comedy · Science Fiction
The Monkey
2025 · Osgood Perkins
When twin brothers find a mysterious wind-up monkey, a series of outrageous deaths tear their family apart. Twenty-five years later, the monkey begins a new killing spree forcing the estranged brother
In common: Comedy · Horror
Pixels
2015 · Chris Columbus
Video game experts are recruited by the military to fight 1980s-era video game characters who've attacked New York.
In common: Comedy · Science Fiction
Lilo & Stitch
2002 · Dean DeBlois
As Stitch, a runaway genetic experiment from a faraway planet, wreaks havoc on the Hawaiian Islands, he becomes the mischievous adopted alien "puppy" of an independent little girl named Lilo and learn
In common: Comedy
Poor Things
2023 · Yorgos Lanthimos
Brought back to life by an unorthodox scientist, a young woman runs off with a lawyer on a whirlwind adventure across the continents. Free from the prejudices of her times, she grows steadfast in her
In common: Comedy · Science Fiction
Mars Attacks!
1996 · Tim Burton
A fleet of Martian spacecraft surrounds the world's major cities and all of humanity waits to see if the extraterrestrial visitors have, as they claim, "come in peace." U.S. President James Dale recei
In common: Comedy · Science Fiction
Lilo & Stitch 2: Stitch Has a Glitch
2005 · Michael LaBash
Now, we find the rowdy extraterrestrial getting used to life with his new ʻohana. However, a malfunction in the ultimate creation of Dr. Jumba soon emerges, which reinstates his destructive programmin
In common: Comedy
Little Shop of Horrors
1986 · Frank Oz
Seymour Krelborn is a nerdy orphan working at Mushnik's; a flower shop in urban Skid Row. He harbors a crush on fellow co-worker, Audrey Fulquard, and is berated by Mr. Mushnik daily. One day, Seymour
In common: Comedy · Horror
The Frighteners
1996 · Peter Jackson
Once an architect, Frank Bannister now passes himself off as an exorcist of evil spirits. To bolster his facade, he claims his "special" gift is the result of a car accident that killed his wife. But
In common: Comedy · Horror
The Babysitter: Killer Queen
2020 · McG
Two years after defeating a satanic cult led by his babysitter Bee, Cole's trying to forget his past and focus on surviving high school. But when old enemies unexpectedly return, Cole will once again
In common: Comedy · Horror
Fright Night
1985 · Tom Holland
Charley Brewster, a high school student, accidentally discovers the true and creepy nature of Jerry Dandrige, his dashing and enigmatic new neighbor; but no one seems willing to believe him.
In common: Comedy · Horror
Ready or Not
2019 · Tyler Gillett
A young bride's wedding night turns into her worst nightmare when her ridiculously rich in-laws force her to play a gruesome game of hide-and-seek.
In common: Comedy · Horror
Jennifer's Body
2009 · Karyn Kusama
Jennifer, a gorgeous, seductive cheerleader takes evil to a whole new level after she's possessed by a sinister demon. Now it's up to her best friend to stop Jennifer's reign of terror before it's too
In common: Comedy · Horror
Scouts Guide to the Zombie Apocalypse
2015 · Christopher Landon
Three scouts and lifelong friends join forces with one badass cocktail waitress to become the world’s most unlikely team of heroes. When their peaceful town is ravaged by a zombie invasion, they’ll f
In common: Comedy · Horror
The Menu
2022 · Mark Mylod
A young couple travels to a remote island to eat at an exclusive restaurant where the chef has prepared a lavish menu, with some shocking surprises.
In common: Comedy · Horror
Tusk
2014 · Kevin Smith
When his best friend and podcast co-host goes missing in the backwoods of Canada, a young guy joins forces with his friend's girlfriend to search for him.
In common: Comedy · Horror
Piranha 3D
2010 · Alexandre Aja
Each year the population of sleepy Lake Victoria, Arizona explodes from 5,000 to 50,000 residents for the annual Spring Break celebration. But then, an earthquake opens an underwater chasm, releasing
In common: Comedy · Horror
The Babysitter
2017 · McG
When Cole stays up past his bedtime, he discovers that his hot babysitter is part of a Satanic cult that will stop at nothing to keep him quiet.
In common: Comedy · Horror
An American Werewolf in London
1981 · John Landis
American tourists David and Jack are savagely attacked by an unidentified animal while hiking on the Yorkshire Moors. After retiring to the home of a beautiful nurse to recuperate, David soon begins e
In common: Comedy · Horror
Braindead
1992 · Peter Jackson
When a Sumatran rat-monkey bites Lionel Cosgrove's mother, she's transformed into a zombie and begins killing (and transforming) the entire town while Lionel races to keep things under control.
In common: Comedy · Horror
Alien: Romulus
2024 · Fede Álvarez
While scavenging the deep ends of a derelict space station, a group of young space colonizers come face to face with the most terrifying life form in the universe.
In common: Horror · Science Fiction
The Human Centipede (First Sequence)
2009 · Tom Six
During a stopover in Germany in the middle of a carefree road trip through Europe, two American girls find themselves alone at night when their car breaks down in the woods. Searching for help at a ne
In common: Horror
Dawn of the Dead
2004 · Zack Snyder
A group of survivors take refuge in a shopping mall after the world is taken over by aggressive, flesh-eating zombies.
In common: Horror · Science Fiction
Brightburn
2019 · David Yarovesky
What if a child from another world crash-landed on Earth, but instead of becoming a hero to mankind, he proved to be something far more sinister?
In common: Horror · Science Fiction
Splice
2010 · Vincenzo Natali
Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "
In common: Horror · Science Fiction
Dawn of the Dead
1978 · George A. Romero
During an ever-growing epidemic of zombies that have risen from the dead, two Philadelphia SWAT team members, a traffic reporter, and his television-executive girlfriend seek refuge in a secluded shop
In common: Horror · Science Fiction
Alien: Covenant
2017 · Ridley Scott
The crew of the colony ship Covenant, bound for a remote planet on the far side of the galaxy, discovers what they think is an uncharted paradise but is actually a dark, dangerous world.
In common: Horror · Science Fiction
Shaun of the Dead
2004 · Edgar Wright
Shaun lives a supremely uneventful life, which revolves around his girlfriend, his mother, and, above all, his local pub. This gentle routine is threatened when the dead return to life and make strenu
In common: Comedy · Horror
The Cloverfield Paradox
2018 · Julius Onah
Orbiting above a planet on the brink of war, scientists test a device to solve an energy crisis and end up face-to-face with a dark alternate reality.
In common: Horror · Science Fiction